All you need to know about the house dust mite
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Why ventilate your home against house dust mites?


Stored at room temperature house dust mite (HDM) droppings remain intact for several months with the major mite allergen Der p1 remaining capable of harming skin, nasal passages or lungs. Ventilation can reduce the risk.

Scientists have repeatedly found that the reduction of indoor humidity through the use of ventilation systems is associated with lower exposure to dust mites and allergens. They have also shown that HDM droppings can remain intact for several months at room temperature.

Without ventilation the droppings, released by activity, are free to roll around on smooth flooring or become part of a dust-bunny, or 'snagged' in carpets or cloth. Good, appropriate ventilation (e.g. by opening windows, using extractor fans in the bathroom and kitchen) can reduce humidity, reduce the risk from molds and contact with HDM droppings, a known risk factor for allergic sensitization.

Warning: Der p1 when activated releases 3 other enzymes held in the dropping and helps to power-up a simple protein to be a major allergen Der p2. This is before it reaches the barrier cells on skin, in the nose and lungs to potentially cause irritation or immune reactions. Der p1 is an enzyme similar to a meat tenderiser used in the food industry (papain) and similar to an enzyme made by the mange mite P ovis to cause itchy sores in sheep. Avoidance of HDM contact is the first step in the management of HDM related disease.

In clinical studies central heating was both negatively and positively associated with house dust mite concentrations. This may be due in part to patterns of use in different parts of the world, as well as comparisons of central heating with different types of heating. Centrally heated homes may be less ventilated because there is a tendency to keep windows closed if the heating is on. In one study the presence of open fireplaces in the living room was associated with a lower concentration of Der p1. The fireplaces usually were not used, but represented a ventilation factor rather than a heating factor.

How ventilation becomes the essential part of a healthy indoor environment is the choice of homeowners, schools and employers. There is a wide range of expert advice available, including (weather permitting) opening windows to send harmful dust outdoors where it won't threaten or harm the vulnerable; the purpose of ventilation.


References

Cambridge University Hospital, "How to reduce levels of Dust Mites in your home" 14/08/2025, www.cuh.nhs.uk/contact-enquiries

Protease allergens as initiators-regulators of allergic inflammation Soh et al, Allergy, 2023 Vol 78,Issue 5, p148-168 "...Der p1 remains activatable in HDM fecal pellets stored at room temperature for several months and remains able to cleave interepithelial tight junctions.”

Wan H et al Der p1 facilitates transepithelial allergen delivery by disruption of tight junctions. J Clin Invest. 1999.104(1): 123-133. doi:10.1172/JC15844

'Dust Mites', Matthew J. Colloff, 2009, Chapter 8, Allergy and epidemiology, (e) heating and ventilation. CSIRO Publishing, Collingwood, Australia, ISBN 978-0-6430-6589-5, Springer ISBN 978-90-481-2223-3