2010 Non-IgE reactions from dust mites

In this subset of atopic mite allergic patients they added non-IgE inflammatory 'load' plus the possibility of aspirin enhanced gut permeability (leading to greater food sensitivity) is key to their investigation. Identification of patients 'at risk' and blocking of leukotriene receptors is one future solution identified by the research team.

They base their investigation on recent research that demonstrated that mite and 'Aspergillus fumigatus' extracts stimulate the increased production of non-IgE (cysteinyl leukotriene) inflammation from bone marrow-derived dendritic cells and pulmonary CD11c+cells.

In a separate study doctors consider that Group II allergens from dust mites have properties that can survive the baking process. They are stable from heat, to extremes of PH, and to digestion by proteases.