All you need to know about the house dust mite
Dust Mite Studies

Medical and scientific quotes for students investigating mites.

The following quotes are from published papers. Copies of the papers can be obtained from medical libraries or from referenced sources.

1989 'The acarine family Pyroglyphidae contains primarily nidicolous mites, so designated because they live in association with birds and mammals (nests, burrows, homes) these vertebrates or their activities provide a food source for the mites' (1)

1989 'The role of mites of the family Pyroglyphidae as the single most important source of house dust allergens was established 20 years ago. Since that time, evidence for sensitisation of patients with asthma to mite allergens has been reported from many different parts of the world. In addition, there has been steady progress in our understanding of the way in which allergens, particularly allergens derived from dust mites, can contribute to asthma, rhinitis [hay fever] and atopic dermatitis'. World Health Organisation supported (2)

1995 'Allergic asthma is a worldwide problem of considerable clinical importance. Links between asthma and exposure to house dust mites have been recognised for more than 300 years. More recently, causal links have been proven between immunity to house dust mites and allergic disorders, including asthma, rhinitis, dermatitis and conjunctivitis' (3)

1998 'At least four of the 'Dermatophagoides pteronyssinus' house dust mite allergens are proteinases. Der p1 is a cysteine proteinase and Der p3, 6 and 9 are serine proteinases. These proteins thus fulfil a criteria of both allergens and proallergic adjuvants' (4)

2000 'Many studies demonstrate the important role allergens play not only in the initiation of asthma but also in its persistence. The severity of asthma in adults and children is related to the level of allergen exposure. Asthma symptoms and bronchial hyperresponsiveness are improved by the reduction of allergen exposure' (5)

2008 'From the early 1960s, considerable literature has been published concerning the taxonomy, biology, immunochemistry and control of mites implicated in allergic reactions. The main source of allergens in house dust in the United States are the mites species 'D. pteronyssinus', 'D farinae' and 'B tropicalis'.' (6)

2013 'Cross-antigenicity between allergens of house dust mites and other parasitic psoroptidians [ sheep mange mite 'P. ovis'] is not surprising given their close phylogenetic affinities.'(7)


References

  1. Biology and Ecology of House Dust Mites Dermatophagoides spp. and Euroglyphus spp.Professor L.G. Arlain, Immunology and Allergy Clinics of North America, 1989, Vol.9, No2, pages 339-355
  2. Dust Mite Allergens and Asthma, A Worldwide Problem, 'The Journal of Allergy and Clinical Immunology', 1989, Vol. 83, pages 416-429
  3. A Major House Dust Mite Allergens Disrupts the Immunoglobulin E Network by Selectively Cleaving CD23, Innate Protection by Antiproteases, Hewett CRA, Brown AP, Hart BJ, Pritchard DI, J. Exp. Med., 1995 Vol 182, pages 1537-1544
  4. Mite allergens significance of enzymatic activity, Hewitt CRA et al, Allergy 1998, Vol. 53, Suppl. 48, pages 60-63
  5. The importance of allergens in the development of asthma, 'Journal of Allergy and Clinical Immunology', Dr Harold S Nelson, 2000, Vol. 105, No 6, part 2, Supp 5 pages 628 to 632
  6. Mite Allergens, Enique Fernandez-Caldas, Leonardo Puerta , Luis Caraballo, Richard R Lockey, 'Clin Allergy Immunol', 2008,21:161-182
  7. 'Is Permanent Parasitism Reversible? - Critical Evidence from Early Evolution of House Dust Mites', Pavel B Klimov, Barry O'Connor, Oxford University Press, on behalf of the Society of Systemic Biologists, published Feb. 15 2013