All you need to know about the house dust mite
Dust Mite Studies

All about house dust mite droppings

House dust mite droppings consist of 3 to 5 food balls bound together by mucus. Each ball is wrapped in a semipermeable membrane. The dropping, containing scraps of undigested food and digestive enzymes, is then excreted. The enzymes help turn leftovers into future food for the mite. A healthy mite can produce up to twenty droppings a day.
Once out of the mite's body the dropping will be held together until it is either eaten by the mite, dissolved upon contact with moisture or broken up by disturbance.

The average intact mite dropping is 10 to 40 microns in size. However, in one research paper scientists observed airborne particles containing mite allergens that ranged from 5 to 40 microns. These were described as either faeces, fibres or flakes of translucent particles.

There may be over 14 separate, fully identified allergens, within one dropping. The latest identified allergen (Der p23) is part of the film that covers the mite's dropping and is consider to be highly allergenic.

To date scientists have identified over 7 different active enzymes from house dust mites.

Particle size matters for people who are sensitive to house dust mites because the smaller the faecal particle carrying active enzymes, the deeper it can travel into the lungs, even reaching delicate areas of gas exchange.


Section of the human lung


In general, inhaled particles above 10 microns will land on the trachea or bronchi while smaller dust (below 10 microns) has the potential to reach and be deposited in the alveoli. The alveoli is the last stop in the branches of our lungs and where gases are exchanged.


References

'Mite allergen (Der p1) is not only carried on mite feces', Sandra De Lucca, Richard Sporik, Timothy J. O;Meara, Euan R. Tovey, 'J Allergy Clin, Immunol.', 1999, 103: 174-5

'Nitric oxide production by alveolar macrophanes in response to house dust mtie fecal pettets and the mite allergens, Der p1 and Der p2\', Peak HL, Currie AJ, Stewart GA, Mc William AS, 2003, 'J. Allergy Clin. Immunol.', Vol. 112, Number 3, p 531-537

'Mechanisms of particulate matter toxicity', S. Salvi, ST Holgate, 1999, 'Clin. Exp. Allergy', Vol. 29, p 1187-1194

'Mite Allergens', Enrique Fernandez-Caldas, Leonardo Puerta, Luis Caraballo, Richard F Lockey, 'Clin. Allergy Immunol.', 2008; 21: p 161-182

Identification of Der p23, A Peritrophin-like Protein, as a New Major Dermatophagoides pteronyssinus Allergen Associate with the Peritrophic Matrix of Mite Fecal Pellets. Weghofer M, J. Immunoloy, April 1, 2013, Vol.190, no.7, 3059-3067